B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice were derived from mating B-hPD-1/hPD-L1/hLAG3 plus mice (130572)and B-hVSIG4 mice (111035) together. For validation data of this mouse model, you can refer to the validation data from the related gene humanized mouse models.